Sandrina Alves Heleno, graduated in Biotechnologic Engineering at the Polytechnic Institute of Bragança in 2008, obtain her master degree in Biotechnology also at Polytechnic Institute of Bragança in 2010, and finish her PhD in Sciences- Chemistry at the University of Minho in 2014. She is currently a postdoctoral fellow at the CIMO and LSRE research centers. Her research interests are: Extraction, purification and characterization of bioactive compounds such as mycosterols present in mushrooms; Bioactivity of the extracts and isolated compounds of mushrooms: antioxidant, antitumor, antimicrobial; hypocholesteremic and anti-inflammatory activities; Development of novel functional foods through the incorporation of extracts and bioactive compounds into dairy products; Stabilization of extracts and compounds in foodstuff. At the moment she has 1 patent, 25 publications in indexed journals of high impact index, 3 book chapters and about 60 communications in national and international conferences, having been member as investigator of 4 research projects. She has also been supervising Master and bachelor students. (ORCID:; ResearcherID: L-5951-2014; Scopus Author ID: 30067731800; H-index: 13).

Supervisors: Isabel Ferreira (CIMO, IPB), Filomena Barreiro, Alírio Rodrigues


I.C.F.R. Ferreira, L. Barros, S. Heleno, M.A.P. Lage, M.F. Barreiro, Obtenção de um aditivo natural à base de catequina a partir de frutos de Arbutus unedo L.. Portuguese Patent 109361, November 2017.
I.C.F.R. Ferreira, S. Heleno, L. Barros, M.F. Barreiro, M.A.P. Lage, Novo produto lácteo funcionalizado com micosteróis como agentes hipocolesterémicos. Portuguese Patent 109089, June 2017.
I.C.F.R. Ferreira, L. Barros, S. Heleno, M.A.P. Lage, M.F. Barreiro, C.M.L.F. Roriz, Gomphrena globosa L.: uma fonte alternativa e promissora para a obtenção de corantes naturais. Portuguese Patent 109174, August 2017.


S.A. Heleno, A.R. Rudke, R.C. Calhelha, M. Carocho, L. Barros, O.H. Gonçalves, M.F. Barreiro, I.C.F.R. Ferreira. Development of dairy beverages functionalized with pure ergosterol and mycosterol extracts: an alternative to phytosterol-based beverages. Food & Function, 8, 103-110, 2017 O. Taofiq, S.A. Heleno, R.C. Calhelha, M.J. Alves, L. Barros, M.F. Barreiro, A.M. González-Paramás, I.C.F.R. Ferreira. Development of Mushroom-Based Cosmeceutical Formulations with Anti-Inflammatory, Anti-Tyrosinase, Antioxidant, and Antibacterial Properties. Molecules, 21, 1372, 2016 S.A. Heleno, P. Diz, M.A. Prieto, L. Barros, A. Rodrigues, M.F. Barreiro, I.C.F.R. Ferreira. Optimization of ultrasound-assisted extraction to obtain mycosterols from Agaricus bisporus L. with response surface methodology and comparison with conventional Soxhlet extraction. Food Chemistry, 197, 1054-1063, 2016 O. Taofiq, R.C. Calhelha, S. Heleno, L. Barros, A. Martins, C. Santos-Buelga, M.J.R.P. Queiroz, I.C.F.R. Ferreira. The contribution of phenolic acids to the anti-inflammatory activity of mushrooms: screening in phenolic extracts, individual parent molecules and synthesized glucuronated and methylated derivatives. Food Research International, 76, 821-827, 2015 I.C.F.R. Ferreira, S.A. Heleno, F.S. Reis, D. Stojkovic, M.J.R.P. Queiroz, M.H. Vasconcelos, M. Sokovic. Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activity. Phytochemistry, 114, 38-55, 2015 S.A. Heleno, A. Martins, M.J.R.P. Queiroz, I.C.F.R. Ferreira. Bioactivity of phenolic acids: metabolites versus parent compounds. Food Chemistry, 173, 501-513, 2015
Sandrina Heleno
Postdoctoral Researcher