Cork corresponds to the bark of the cork oak (Quercus Suber L.). It is an exceptional material that conceals high-value products. This research area aims at developing a sustainable and clean process, completely integrated in the traditional industrial cork facilities, to use the granulated cork as a source of bioactive compounds with promising applications (as friedelin, cerine, betulinic acid, betulin, etc.); this new process could constitute a push-forward for the cork industry, expanding its products and markets. Several samples of granulated industrial cork and cork powder were extracted using two different technologies, soxhlet that constitute a benchmark extraction process and supercritical fluid extraction (SFE) using CO2 with and without co-solvent. The results obtained by the research team show that it is possible to add a new value to cork. At the moment, the work is focused in optimizing the process in order to increase the yields using green solvents.