Madalena Dias graduated in Chemical Engineering at the Faculty of Engineering of the University of Porto (FEUP) in 1977 and joined the Department of Chemical Engineering of FEUP as Teaching Assistant. In 1979 she started her post-graduate studies in the Department of Chemical Engineering from the University of Houston, Texas, USA, where in 1984 she obtained her degree of Ph.D. in the area of Simulation of Flow in Porous Media. Between 1984 and 1988 she worked as a Research Scientist at the multinational company Schlumberger Ltd., first at Schlumberger-Doll Research, in Ridgefield, Connecticut, USA and later at Schlumberger Cambridge Research, Cambridge, UK, conducting research in the area of Characterization and Simulation of Flow in Oil Reservoirs. In 1988 she returned to FEUP where she pursues her teaching and research career. From 2005 to 2010 she was part of the team that founded Fluidinova, SA, a spin-off company of LSRE-LCM. In January 2013, she assumed the direction and scientific coordination of LSRE-LCM.


Mixing in chemical reactors
- Micro/Meso structured reactors; NETmix
Process modelling and simulation
- Network Modelling
Nanoparticle materials industrial production processes


J.C.B. Lopes, M.M.G.Q. Dias, V.M.T.M. Silva, P.A.Q.O. Santos, F.J.M. Monteiro, P.J.C. Gomes, A.Y.P. Mateus, Production Method for Calcium Phosphate Nano-Particles with High Purity and their Use. PCT/PT2007/000031, July 2007. US Patent 12159696, April 2009. EU Patent 2041025, July 2008. Portuguese Patent WO/2008/007992, July 2006.
J.C.B Lopes, P.E.M.S.C. Laranjeira, M.M.Q. Dias, A.A.A.Martins, Network Mixer and Related Mixing Process. PCT/IB2005/000647, February 2005. US Patent 8434933 B2, September 2008, granted May 2013. EU Patent 1720643, September 2006, granted October 2008. Portuguese Patent 103072, February 2004, granted December 2009.


G. Ruphuy, T. Weide, J.C.B. Lopes, M.M. Dias, M.F. Barreiro. Preparation of nano-hydroxyapatite/chitosan aqueous dispersions: From lab scale to continuous production using an innovative static mixer. Carbohydrate Polymers, 202, 20-28, 2018 G. Ruphuy, M. Souto-Lopes, D. Paiva, P. Costa, A.E. Rodrigues, F.J. Monteiro, C.L. Salgado, M.H. Fernandes, J.C. Lopes, M.M. Dias, M.F. Barreiro. Supercritical CO2 assisted process for the production of high-purity and sterile nano-hydroxyapatite/chitosan hybrid scaffolds. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 106, 965-975, 2018 M.F. Costa, C.M. Fonte, M.M. Dias, J.C.B. Lopes. Heat Transfer Performance of NETmix — A Novel Micro-Meso Structured Mixer and Reactor. AIChE Journal, 63, 2496-2508, 2017 M.J. Lima, C.G. Silva, A.M.T. Silva, J.C.B. Lopes, M.M. Dias, J.L. Faria. Homogeneous and heterogeneous photo-Fenton degradation of antibiotics using an innovative static mixer photoreactor. Chemical Engineering Journal, 310, 342–351, 2017 B.A. Marinho, R. Djellabi, R.O. Cristóvão, J.M. Loureiro, R.A.R. Boaventura, M.M. Dias, J.C.B. Lopes, V.J.P. Vilar. Intensification of heterogeneous TiO2 photocatalysis using an innovative micro-meso-structured-reactor for Cr(VI) reduction under simulated solar light. Chemical Engineering Journal, 318, 76-88, 2017 G. Ruphuy, A. Saralegi, J.C. Lopes, M.M. Dias, M.F. Barreiro. Spray drying as a viable process to produce nano-hydroxyapatite/chitosan (n-HAp/CS) hybrid microparticles mimicking bone composition. Advanced Powder Technology, 27, 575–583, 2016 C.M. Fonte, M.E. Leblebici, M.M. Dias, J.C.B. Lopes. The NETmix reactor: Pressure drop measurements and 3D CFD modeling. Chemical Engineering Research and Design, 91, 2250-2258, 2013 M.I. Nunes, R.J. Santos, M.M. Dias, J.C.B. Lopes. Micromixing assessment of confined impinging jet mixers used in RIM. Chemical Engineering Science, 74, 276-286, 2012 P.E. Laranjeira, A.A. Martins, M.I. Nunes, J.C.B. Lopes, M.M. Dias. NETmix®, a new type of static mixer: Experimental characterization and model validation. AIChE Journal, 57, 1020-1032, 2011 P.E. Laranjeira, A.A. Martins, J.C.B. Lopes, M.M. Dias. NETmix®, A New Type of Static Mixer: Modeling, Simulation, Macromixing, and Micromixing Characterization. AIChE Journal, 55, 2226-2243, 2009 P.J. Gomes, V.M.T.M. Silva, P.A. Quadros, M.M. Dias, J.C.B. Lopes. A Highly Reproducible Continuous Process for Hydroxyapatite Nanoparticles Synthesis. Journal of Nanoscience and Nanotechnology, 9, 3387-3395, 2009 V.G. Mata, J.C.B. Lopes, M.M. Dias. Porous Media Characterisation Using Mercury Porosimetry Simulation. 2: An Iterative Method for the Determination of the Real Pore Size Distribution and the Mean Coordination Number. Industrial & Engineering Chemistry, 40, 4836-4843, 2001


Valor Natural - Natural Resources through the Extraction of High Added Value Ingredients for Applications in the Food Industry. Reference: NORTE-01-0247-FEDER-024479. Funded by: ANI – Agência Nacional de Investigação, P2020|COMPETE - Programas Mobilizadores. Starting Date: 2018/09/01. Duration: 36 months. Role: Coordinator NoMIC2Bone - NanoXIM® Based Antimicrobial Structures for Bone Regeneration. Reference: NORTE-01-0247-FEDER-017905. Funded by: ANI – Agência Nacional de Investigação, P2020|COMPETE - Projetos em Copromoção. Starting Date: 2017/07/01. Duration: 36 months. Role: Coordinator UnirCell - Unitised regenerative fuel cell for efficient renewable energy supply: from materials to device. Reference: POCI-01-0145-FEDER-016422. Funded by: FCT – Fundação para a Ciência e a Tecnologia, PAC - P2020|COMPETE -Programa de Ações Conjuntas. Starting Date: 2017/01/01. Duration: 48 months. Role: Researcher AIProcMat@N2020 - Advanced Industrial Processes and Materials for a Sustainable North Region of Portugal2020. Reference: NORTE-01-0145-FEDER-000006. Funded by: CCDR-N - Comissão de Coordenação e Desenvolvimento Regional do Norte, P2020|Norte2020 - Projetos Integrados ICDT. Starting Date: 2016/06/01. Duration: 36 months. Role: Coordinator TexBioPro - Functionalization of textile substrates with biodegradable microparticles produced by continuous processes. Reference: POCI-01-0247-FEDER-003472. Funded by: ANI – Agência Nacional de Investigação, P2020|COMPETE - Projetos em Todos os Domínios Científicos. Starting Date: 2016/04/01. Duration: 36 months. Role: Coordinator RL2_P2 - Mixing in Chemical Reactors. Reference: NORTE-07-0124-FEDER-000013. Funded by: CCDR-N, Programa Operacional Regional do Norte (ON.2). Starting Date: 2014/01/01. Duration: 18 months. Role: Coordinator SolarNETmix - Solar-Driven Catalytic NETmix® Reactor. Reference: PTDC/EQU-ERQ/123045/2010. Funded by: FCT – Fundação para a Ciência e a Tecnologia, I&DT - Projectos de I&DT em Todos os Domínios Científicos. Starting Date: 2012/03/31. Duration: 40 months. Role: Coordinator FluSHELL - Development of a Thermo-Hydraulic Network Model for SHELL Type Power Transformers. Reference: FEUP/EFACEC/2011/03. Funded by: EFACEC Energia. Starting Date: 2011/04/29. Duration: 24 months. NETmix-NanoHAp - NETmix Reactor for Production of Hydroxyapatite Nanoparticles. Reference: DEMTEC 70/00224. Funded by: ANI – Agência Nacional de Investigação, DEMTEC - Projectos Demonstradores. Starting Date: 2007/07/01. Duration: 24 months.
Madalena Dias
Professor Associado